To improve latency and to store data in a location that meets your requirements, Amazon SimpleDB enables you to select different region endpoints.
For information about this Amazon SimpleDB regions and endpoints, go to Regions and Endpoints in the Amazon Web Services General Reference.
For example, to create a SimpleDB domain in Europe, you would generate a REST request similar to the following:
https://sdb.eu-west-1.amazonaws.com/?Action=CreateDomain &DomainName=MyDomain &<authentication parameters>
Each Amazon SimpleDB endpoint is entirely independent. For example, if you have two domains called "MyDomain," one in sdb.amazonaws.com and one in sdb.eu-west-1.amazonaws.com, they are completely independent and do not share any data.