Amazon Route 53
Developer Guide (API Version 2013-04-01)

Migrating DNS Service for an Existing Domain to Amazon Route 53

You can migrate DNS service for an existing domain to Route 53. The process depends on whether you're currently using the domain:

For both options, your domain should remain available during the entire migration process. However, in the unlikely event that there are issues, the first option lets you roll back the migration quickly. With the second option, your domain could be unavailable for a couple of days.