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Document history for the HealthOmics User Guide - AWS HealthOmics

Document history for the HealthOmics User Guide

The following table describes the documentation releases for HealthOmics.

ChangeDescriptionDate

New Feature

With expanded container registry support, you can use container images from registries such as Seqera Containers, NVIDIA NGC, and Google Artifact Registry with AWS HealthOmics private workflows, without manually migrating images into Amazon ECR or editing your workflow definitions. To learn more, see Using third-party registries not supported by pull through cache.

October 14, 2026

New Feature

HealthOmics added the omicsResourceFallbackOrder directive for WDL and Nextflow workflows. Use it to list resource profiles in order of preference, so that a task falls back to an alternate accelerator type, or to CPU, when the preferred capacity isn't available. To learn more, see Advanced resource configuration.

October 13, 2026

New Content

HealthOmics added a guide for running Illumina DRAGEN software mode in private workflows. To learn more, see Illumina DRAGEN on HealthOmics private workflows.

October 9, 2026

New Feature

HealthOmics published a change log for the WDL engine, covering new features, enhancements, and behavior changes for the default WDL engine and WDL lenient mode. To learn more, see WDL engine change log for HealthOmics.

September 22, 2026

New Feature

HealthOmics added support for Nextflow profiles from API, which lets you select environment-specific configuration at runtime using the engineSettings parameter. To learn more, see Use Nextflow profiles.

June 1, 2026

New Feature

HealthOmics added support for batch runs, which let you submit up to 100,000 workflow runs in a single API request. To learn more, see Batch runs in HealthOmics.

March 20, 2026

AWS HealthOmics variant stores and annotation stores are no longer open to new customers.

AWS HealthOmics variant stores and annotation stores are no longer open to new customers. For more information, see AWS HealthOmics variant store and annotation store availability change.

November 7, 2025

AWS HealthOmics variant stores and annotation stores will no longer be open to new customers starting November 7th, 2025.

AWS HealthOmics variant stores and annotation stores will no longer be open to new customers starting November 7th, 2025. If you would like to use variant stores or annotation stores, sign up prior to that date. Existing customers can continue to use the service as normal. For more information, see AWS HealthOmics variant store and annotation store availability change.

October 7, 2025

New Features

HealthOmics added support for workflows to synchronize a private Amazon ECR repository with an upstream registry. To learn more, see Container images for private workflows in HealthOmics.

August 28, 2025

New README and repository integration features

Added support for creating workflows from external code repositories and README files.

July 24, 2025

New Features

HealthOmics added support for Nextflow automatic parameter interpolation. To learn more, see Parameter template files for HealthOmics workflows.

June 27, 2025

New Features

HealthOmics added support for workflows to interpolate the run parameters from a WDL workflow definition file. To learn more, see Parameter template files for HealthOmics workflows.

May 30, 2025

New Features

HealthOmics added support for workflow versioning. To learn more, see Workflow versioning in HealthOmics.

April 18, 2025

New Features

HealthOmics added elastic throughput for dynamic run storage. To learn more, see Run storage types in HealthOmics.

April 16, 2025

New Features

HealthOmics added attribute based access controls for Sequence Store S3 locations, and the abilty to synchronize up to five read-set tags to a Sequence Store S3 object. To learn more, see Creating a HealthOmics sequence store.

November 22, 2024

New Features

HealthOmics added support for call caching, also known as resume, for private workflows. To learn more, see Call caching.

November 20, 2024

New Features

HealthOmics added new API fields to help you map between sequence store input jobs and read sets.

August 29, 2024

New Features

HealthOmics added support for managing Nextflow versions. To learn more, see Nextflow versions.

August 14, 2024

New Features

HealthOmics added support for shared workflows and dynamic run storage.

April 30, 2024

New Features

HealthOmics added support for Amazon S3 access to reference and sequence stores, and support for SHA256 ETags.

April 15, 2024

New Features

HealthOmics added entity tags (ETags) for sequence stores.

October 6, 2023

New Features

HealthOmics added annotation store versioning and analytic store sharing.

August 15, 2023

New Features

HealthOmics added Common Workflow Language (CWL) as a supported language for HealthOmics workflows.

June 30, 2023

New Features

HealthOmics added new Ready2Run workflows, GPU support for workflows, data parsing for annotation stores, direct upload into HealthOmics storage, and integration with EventBridge.

May 15, 2023

New managed policy

HealthOmics added a new managed policy that provides full access. To learn more, see AWS managed policies.

February 23, 2023

New managed policy

HealthOmics added a new managed policy that limits access to read only. To learn more, see AWS managed policies.

November 29, 2022

Initial release

Initial release of the HealthOmics User Guide

November 29, 2022